| .EPS | Encapsulated PostScript File | 237 |
| .EXE | Windows Executable File | 172 |
| .EPUB | Open eBook File | 237 |
| .EML | E-Mail Message | 254 |
| .EMF | Enhanced Windows Metafile | 324 |
| .ENC | Encoded File | 230 |
| .EMZ | Windows Compressed Enhanced Metafile | 247 |
| .EXIF | Exchangeable Image Information File | 371 |
| .EXE | PortableApps.com Application | 229 |
| .EPW | EnergyPlus Weather Data File | 200 |
| .EDRW | SolidWorks eDrawings File | 400 |
| .EFX | eFax Document | 267 |
| .EMP | eMusic Music Download File | 250 |
| .EMX | eMusic Download File | 220 |
| .ERF | BioWare Entity Resource File | 260 |
| .EXP | Symbols Export File | 262 |
| .ELF | Executable and Linkable Format File | 225 |
| .EDJ | Enlightenment Theme File | 200 |
| .ESM | Elder Scrolls Master File | 187 |
| .ECM | ECM Disc Image | 219 |
| .EDL | Edit Decision List File | 367 |
| .ENEX | Evernote Archive | 287 |
| .EAR | Java Enterprise Archive File | 200 |
| .ENL | EndNote Library | 212 |
| .ERB | Ruby ERB Script | 167 |
| .EDI | Electronic Data Interchange File | 200 |
| .EX01 | EnCase Evidence Image File | 133 |
| .EX5 | MetaTrader 5 Program File | 250 |
| .ERR | Error Log File | 240 |
| .EXD | Control Information Cache File | 225 |
| .ENT | External Entity | 383 |
| .EV | Echoview File | 250 |
| .EQP | MathType Preferences | 167 |
| .EQL | MathType Settings | 300 |
| .ECF | Outlook Add-in | 189 |
| .EQL | Embedded SQL File | 300 |
| .EMD | ChessBase Tablebase | 257 |
| .EAP | Enterprise Architect Project | 244 |
| .EYE | Eyemail Video Recording File | 440 |
| .EMLX | Mail Message | 250 |
| .EMLXPART | Mail Message Attachment | 300 |
| .EX | Euphoria Source Code | 202 |
| .ETF | ENIGMA Transportable File | 300 |
| .EDA | Ensoniq ASR Disk Image | 250 |
| .EDE | Ensoniq EPS Disk Image | 300 |
| .EDK | Ensoniq KT Disk Image | 400 |
| .EDS | Ensoniq SQ-80 Disk Image | 400 |
| .EDV | Ensoniq VFX-SD Disk Image | 300 |
| .EFA | Ensoniq ASR File | 375 |
| .EFK | Ensoniq KT File | 300 |
| .EFQ | Ensoniq SQ1/SQ2/KS-32 File | 300 |
| .EFS | Ensoniq SQ-80 File | 300 |
| .EFV | Ensoniq VFX-SD File | 300 |
| .EMB | Wilcom Embroidery Design File | 271 |
| .EMD | ABT Extended Module | 250 |
| .ESPS | ESPS Sampled Data File | 300 |
| .EUI | Ensoniq EPS Compacted Disk Image | 300 |
| .EBM | EXTRA! Basic Macro | 229 |
| .ERB | Evil Genius Resource File | 400 |
| .EDB | Exchange Information Store Database | 259 |
| .ENG | Chess Engine | 180 |
| .EFW | Renamed Zip or Executable File | 300 |
| .ECS | Sony Ericsson Phone Backup File | 200 |
| .ELF | PlayStation Executable File | 262 |
| .EFL | Encryptafile Encrypted File | 300 |
| .EXP | Export File | 333 |
| .EBUILD | Portage eBuild Script | 250 |
| .EBN | Philips Firmware Update File | 333 |
| .EXX | IBM Linkway MsgPut File | 200 |
| .EQF | Winamp Equalizer Preset File | 400 |
| .ECO | ECCO Database File | 267 |
| .ECX | ECCO Corrupted Database File | 375 |
| .EVO | HD DVD Video File | 367 |
| .ELF | Nintendo Wii Game File | 198 |
| .EST | Streets & Trips Map File | 300 |
| .EUM | Enterprise User Monitor Configuration File | 300 |
| .EGM | Enigmo Custom Game File | 300 |
| .ESG | Enigmo Saved Game File | 300 |
| .ESPROJ | Espresso Project File | 300 |
| .ECF | SageCRM Component File | 214 |
| .EPIBRW | Web File Location | 233 |
| .ER1 | ERWin Entity Relationship Diagram | 325 |
| .EGG | Panda3D Model File | 286 |
| .EMULECOLLECTION | eMule Data File | 333 |
| .EFTX | Office 2007 Theme Effect File | 229 |
| .EX4 | MetaTrader 4 Program File | 221 |
| .ETD | Adobe Reader EBX Transfer Data File | 360 |
| .ETL | Microsoft Event Trace Log File | 216 |
| .EGP | Easy Grade Pro Gradebook File | 200 |
| .EXE4J | Exe4j Configuration File | 300 |
| .EVT | Windows Event Viewer Log File | 400 |
| .ESX | Xactimate Insurance Claims Estimate | 300 |
| .EPF | Edgecam Educational Part File | 300 |
| .EPSF | Encapsulated PostScript Format File | 300 |
| .EXP | CATIA 4 Export File | 350 |
| .ERF | Epson RAW File | 300 |
| .EZW | easyOFFER Real Estate Form File | 233 |
| .EBK | eBook Pro eBook File | 207 |
| .ECW | Enhanced Compression Wavelet Image | 250 |
| .ENC | Encore Musical Notation File | 322 |
| .EDMX | ADO.NET Entity Data Model Designer File | 200 |
| .E2GM | Pangea Enigmo 2 Custom Game File | 433 |
| .EMC | Striata Reader Encrypted Document | 275 |
| .EX_ | Compressed Executable File | 221 |
| .EAZ | ArcGIS Explorer Add-in File | 200 |
| .ECL | Management-Ware Mass Mailing News E-Campaign List | 400 |
| .EXR | OpenEXR Image | 195 |
| .EXW | Euphoria Source code File | 300 |
| .EDML | Adobe Extension Data Markup Language Document | 300 |
| .EFI | Extensible Firmware Interface File | 208 |
| .ESM | Fallout 3 Master File | 300 |
| .EVTX | Windows 7 Event Log File | 309 |
| .EDRWX | XPS Drawing Document | 300 |
| .EPP | Canon Easy-PhotoPrint Image File | 350 |
| .ESP | Fallout 3 Plugin File | 207 |
| .EFP | Exchange Forms Designer Template | 300 |
| .EWP | Ewisoft Website Project File | 350 |
| .EASM | eDrawings Assembly File | 230 |
| .ESB | Es-Builder Book File | 300 |
| .E01 | EnCase Image File | 217 |
| .EDAT | E-DataAid 1.x File | 300 |
| .EDAT2 | E-DataAid 2.0 File | 300 |
| .ES2 | E-Studio 2.0 Experiment File | 400 |
| .ES | E-Studio 1.x Experiment File | 300 |
| .EBS2 | E-Run 2.0 Script File | 183 |
| .EDGE | Adobe Edge Project File | 300 |
| .ESS | The Elder Scrolls Saved Game | 185 |
| .EDN | EDIF Implementation Netlist File | 220 |
| .EDF | Edificius Project | 250 |
| .EDG | Edge Diagrammer File | 350 |
| .ET | Kingsoft Spreadsheets File | 224 |
| .E57 | LIDAR Point Cloud Data File | 250 |
| .ERL | Erlang Source Code File | 200 |
| .ENLX | Archived EndNote Library | 300 |
| .ENF | EndNote Filter File | 300 |
| .ENS | EndNote Style File | 214 |
| .ENZ | EndNote Connection File | 250 |
| .ERS | ER Mapper Data File | 400 |
| .ESP | Elder Scrolls Plugin File | 165 |
| .EM | Encore Menu Template | 360 |
| .EFIRES | EFI Image File | 367 |
| .EXPORTEDFAVORITES | Transmit Exported Favorites File | 400 |
| .EZT | EZTitles Subtitles File | 360 |
| .ENTITLEMENTS | Mac App Sandboxing Entitlements File | 300 |
| .EGG | ALZip Archive | 350 |
| .EWD | EasyWOOD Design File | 300 |
| .EP | Pencil Document | 240 |
| .EHI | HTTP Injector Config File | 206 |
| .EIP | Enhanced Image Package File | 225 |
| .ESD | Windows Electronic Software Download File | 181 |
| .EZDRAW | EazyDraw Graphic | 400 |
| .EBD | Windows EBD System File | 160 |
| .EGC | EximiousSoft GIF Creator Document | 300 |
| .EDX | Edraw XML FIle | 314 |
| .EDXZ | Edraw Compressed XML FIle | 250 |
| .EIO | Yozo Office File | 222 |
| .ENX | Max PC Safe Encrypted File | 250 |
| .EV3 | LEGO MINDSTORMS EV3 Project | 169 |
| .ENV | Now Contact Envelope Template | 300 |
| .EXPORTEDUI | Microsoft Office Exported UI Customization File | 433 |
| .ELD | Eulumdat Formatted Luminaire Data File | 250 |
| .ESF | Password Manager Container File | 300 |
| .EPF | EAGLE Project | 200 |
| .ESCOPY | ES Explorer Temporary File | 300 |
| .EF | Diploma Exam File | 300 |
| .EPIM | EssentialPIM Database File | 300 |
| .EPP | Elmedia Player Playlist | 300 |
| .EYETV | EyeTV Recording File | 300 |
| .EVO | SeeVogh Player Video Recording | 250 |
| .ESLOCK | ES File Explorer File Manager Encrypted File | 255 |
| .ESCAPE | Prison Architect Escape Mode Save File | 300 |
| .ESC | EasySignCut Pro Project | 250 |
| .EXS | EXS Instrument | 350 |
| .EDZ | EPLAN Electric P8 Data Archive Zipped File | 275 |
| .EDDX | Edraw XML FIle | 243 |
| .EWPRJ | Ultiboard Layout Project | 300 |
| .EMM | MindMaple Map | 350 |
| .EPRT | eDrawings File | 300 |
| .ELS | EasyLanguage Storage File | 300 |
| .ECW | EclipseCrossword Word List File | 300 |
| .ETNG | Easiteach Next Generation Document | 300 |
| .EYB | Microsoft Encarta Yearbook Update File | 400 |
| .E00 | ArcInfo Coverage Export File | 200 |
| .ESP | ACD/Labs Dataset | 325 |
| .EFE | Ensoniq EPS File | 400 |
| .EOT | Embedded OpenType Font | 347 |
| .ERR | FoxPro Compilation Error | 367 |
| .EPP | TalaPhoto Project | 250 |
| .EPP | EditPad Pro Project | 280 |
| .ECE | Escenic Dynamic Web Page | 378 |
| .EFL | External Format Language File | 250 |
| .EFR | Encryptafile Private Key File | 400 |
| .EFU | Encryptafile Public Key File | 400 |
| .EXP | Aurora Expert Trace File | 367 |
| .EXP | SonicWALL Preference File | 400 |
| .EPP | Efficient PPC Project File | 333 |
| .ENC | Copysafe Protected PDF File | 300 |
| .ENC | Electronic Navigation Chart File | 270 |
| .ES | SageCRM Script File | 400 |
| .EEP | EEPROM Data File | 200 |
| .EMERALD | Emerald Theme | 400 |
| .E4A | Encrypt4all Archive | 400 |
| .EPK | Metin2 Game Data Package | 258 |
| .EXS | Blades of Exile Scenario | 350 |
| .EST | Construction Cost Estimate File | 400 |
| .ET | Easiteach Lesson File | 188 |
| .EC0 | MetroCount Traffic Data File | 400 |
| .ETA | Google Earth Placemark File | 275 |
| .EDF | ESRF Data File | 320 |
| .EZT | EZT Malicious Worm File | 333 |
| .EV3 | Team Manager Meet Event File | 317 |
| .EPI | EclipsePackager2000 Compressed File | 400 |
| .EXOPC | ExoPC Application | 400 |
| .EDAT | Sony Encrypted Data File | 380 |
| .EDC | Kryptel Lite Encrypted File | 350 |
| .EAS | RSLogix Symbol File | 267 |
| .EX_ | Renamed Windows Executable File | 197 |
| .ERR | AutoCAD Error Log File | 262 |
| .EAP | Adobe Photoshop Exposure File | 325 |
| .EDM | Adobe Extension Data Markup Language File | 250 |
| .ENV | Adobe Dictionary Data File | 400 |
| .EL | Emacs Lisp Code File | 300 |
| .ELC | Emacs Compiled Lisp File | 450 |
| .ENV | Vue Environment File | 450 |
| .EXPRESSIONMAP | Cubase Expression Map File | 333 |
| .ELM | Office Theme File | 350 |
| .ELM | Eternal Lands Map File | 143 |
| .EQN | GAL Equation File | 300 |
| .ERP | Alter Ego Game Archive | 325 |
| .EXL | Export Lister File | 200 |
| .ECC | dvdisaster Error Correction File | 400 |
| .EZLOG | Skype Extras Manager Log File | 350 |
| .EMB | Pfaff Embroidery Design File | 300 |
| .EXT | Generic Email Attachment | 309 |
| .EMRG2 | E-Merge 2.0 Data File | 400 |
| .EMRG | E-Merge 1.x Data File | 400 |
| .EBS | E-Run 1.x Script | 233 |
| .EPK2 | E-Prime 2.0 Package File | 400 |
| .ECP | EasyC Project File | 400 |
| .EDN | Adobe eBook Activation File | 400 |
| .EWS | EasyWorship Schedule File | 275 |
| .ETT | Kingsoft Spreadsheets Template | 350 |
| .ERL | GameGuard Error Log File | 208 |
| .EF2 | Internet Download Manager Export File | 220 |
| .EZP | AutoCAD Ecscad Project Backup File | 225 |
| .ENQ | EndNote Search Options File | 400 |
| .ETX | TeX Font Encoding File | 250 |
| .E_E | Renamed EXE File | 267 |
| .EMY | eMelody Ringtone File | 400 |
| .EPR | Photoshop AME Preset File | 410 |
| .ENML | Evernote for Android Note | 450 |
| .ERSX | Eraser Task List File | 440 |
| .EC3 | EPSON Print CD File | 250 |
| .EC4 | EPSON Print CD File | 220 |
| .EBM | Embla Recording | 325 |
| .EWB | Electronics Workbench Circuit Design File | 286 |
| .EXM | Boson Exam File | 333 |
| .EUF | Private Character Editor File | 467 |
| .EVENT | Corel Cataloged Folder File | 400 |
| .EST_UAX | Spanish Unreal Audio Package | 400 |
| .EXAMPLE | Example Configuration File | 222 |
| .EXB | CAXA Draft | 360 |
| .EMF | Jasspa MicroEmacs Macro File | 400 |
| .EIT | Yozo Office Template File | 260 |
| .ECT | Yozo Office Chart Template File | 333 |
| .EV3P | LEGO MINDSTORMS EV3 Program | 160 |
| .EV3S | LEGO MINDSTORMS EV3 Shared File | 240 |
| .EOP | EveryonePiano Music Score File | 220 |
| .EFX | Jedi Knight Effects File | 400 |
| .ERB | Braille Music Reader File | 450 |
| .EA | Kindle End Actions File | 400 |
| .EAL | Kindle End Actions File | 400 |
| .EBA | Emergence BASIC Source Code File | 400 |
| .EGT | EagleGet Temporary File | 219 |
| .EYETVSCHED | EyeTV Schedule File | 300 |
| .EYETVP | EyeTV Recording Metadata File | 250 |
| .EXO | YouTube Video Chunk File | 255 |
| .EKX | Encrypted 3DS Pokémon Save File | 157 |
| .EK6 | Generation 6 Pokémon Save File | 450 |
| .EVX | SeeVogh Player Remote Recording | 200 |
| .EMBL | EMBL Sequence Data File | 400 |
| .EMBR | Spatial Geodatabase File | 175 |
| .ENX | eDataSecurity Management Encrypted File | 400 |
| .EXC | eDataSecurity Management Self-extracting File | 400 |
| .EVP | Talisman Online Game Data File | 160 |
| .EL4 | Easy-PhotoPrint EX Calendar File | 400 |
| .EPK | LG Firmware Package | 200 |
| .E2P | PonyProg Device File | 400 |
| .EWL | EclipseCrossword Word List File | 400 |
| .EWNET | Ultiboard Netlist File | 400 |
| .EMMT | MindMaple Map Template | 400 |
| .ECFG | ArcGIS Component Configuration File | 400 |
| .ERD | Entity Relation Diagram | 400 |
| .ERD | Engineering Research Division Data File | 400 |
| .ENV | WordPerfect Environment | 500 |
| .EQN | WordPerfect Equation | 500 |
| .EXT | Norton Commander Extension | 283 |
| .ESH | Extended Shell Batch File | 300 |
| .ETX | Structure Enhanced Text (Setext) File | 350 |
| .EUC | Extended Unix Code File | 300 |
| .EMAIL | Outlook Express Email Message | 300 |
| .EVY | Envoy File | 500 |
| .ESS | EasySpreadsheet Spreadsheet | 340 |
| .EZS | EZ-R Stats Batch Script | 367 |
| .EAR | Eyemail Audio Recording | 400 |
| .EDQ | Ensoniq SQ1/SQ2/KS32 Disk Image | 500 |
| .EMB | Everest Embedded Bank File | 217 |
| .EDF | Estimator Data File | 500 |
| .EIX | Metin2 Game Data File | 223 |
| .EV3 | Everlock Options File | 367 |
| .ENW | EndNote Import File | 274 |
| .EDFX | Estimator.NET Estimate File | 500 |
| .EXC | Black & White Zone File | 367 |
| .ETFF | Encrypt4all Theme File | 500 |
| .EPC | Doctor Who Game Data File | 500 |
| .ESE | Millions Email Generator Email List File | 280 |
| .EXL | JSDAI Inclusion or Exclusion List | 433 |
| .ESQ | Embroidery Sequence File | 500 |
| .ENC | Cabal Online Data File | 252 |
| .EZC | AutoCAD Ecscad Components Backup File | 450 |
| .EHAM | ExtraHAM Executable File | 375 |
| .ENP | EndNote Preferences File | 500 |
| .EEPF | EmuOS Exchangeable Packet File | 500 |
| .EXV | Adobe Extension Script | 500 |
| .EXTRA | Google BreakPad Crash Log Extra File | 262 |
| .EEK | Arachne Network-Enabled Script | 500 |
| .EXE1 | Renamed EXE File | 216 |
| .ECL | Touhou Stage Script | 300 |
| .EVR | Enhanced Variable Rate Audio File | 300 |
| .ERP | Encarta Researcher File | 500 |
| .EGLIB | Adobe Edge Animate Library File | 500 |
| .EKB | ZMC Visual Tablet Data | 500 |
| .EVRC | Enhanced Variable Rate Codec File | 500 |