AutoCAD Custom User Interface File
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What is a CUIX file?
Custom workspace file created by the Custom User Interface (CUI) Editor component of AutoCAD; stores window and palette settings as well as toolbar and menu configurations; may also include custom images; used for loading full or partial custom workspace layouts during a drawing session.
The default CUIX file is acad.cuix, which contains the standard layout that is loaded when AutoCAD is opened for the first time. CUIX files are stored as a package of multiple XML and image files.