.MZML File Extension
Mass Spectrometer Output File
| Developer | HUPO Proteomics Standards Initiative |
| Popularity |
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What is an MZML file?
An MZML file is a mass spectrometer output file saved in the mzML format. It contains XML-formatted mass spectrometry data. The mzML format is standard and open-source, so many mass spectrometry applications can create and open MZML files.
More Information
In June 2008, the HUPO Proteomics Standards Initiative (PSI) finalized and released version one of the mzML format. PSI created this XML-based format to replace two previous, competing mass spectrometer output formats: mzData (developed by PSI) and mzXML (developed by the Seattle Proteome Center). The mzML format incorporates and combines the best features of both mzData and mzXML.
Now, several mass spectrometry applications can save mass spectrometer output data in the mzML format and open MZML files. Thus, analytical chemists and biochemists who plan to share their mass spectrometer output data often save that data in the mzML format.
NOTE: In addition to ion mass-to-charge ratio and intensity data, MZML files can contain metadata about the settings and conditions under which this output data was captured.
How to open an MZML file
You can open an MZML file with several mass spectrometry result analysis programs, including:
- ProteoWizard (Windows, Linux)
- MaxQuant (Windows)
- Skyline (Windows)
These programs allow you to view and analyze the mass spectrometer output data an MZML file contains.
How to convert an MZML file
ProteoWizard's MSConvert module can convert MZML files to several other mass spectrometry output data formats, including:
- mzXML
- mz5
- mzMLb
- mgf
- ms1
- cms1
- ms2
- cms2